Adenoviral Vectors for Gene Therapy

ISBN: 0121995046

Category: Medical

Tag: Medical/Medicine

Posted on 2007-07-06. By anonymous.


Adenoviral Vectors for Gene Therapy

Publisher: Academic Press
Number Of Pages: 890
Publication Date: 2002-05
Sales Rank: 1060419
ISBN / ASIN: 0121995046
EAN: 9780121995041
Binding: Hardcover
Manufacturer: Academic Press
Studio: Academic Press

Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors.

Key Features
* Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors
* Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement
* Demonstrates noninvasive imaging of adenovirus-mediated gene transfer
* Discusses utility of adenoviral vectors in animal disease models
* Considers Federal Drug Administration regulations for human clinical trials

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